The chemical structure of the amino acid Valine is monitored across different environments: Choose the correct option depicting the structures of products A and B under pH = 2 and pH = 10 conditions respectively.

Valine pH equilibrium conversion layout for Q39
The flowchart maps the structural modifications of Valine when treated at strongly acidic (pH = 2) versus basic (pH = 10) conditions.

Solution & Explanation

### Core Logic Amino acids exhibit amphoteric behavior due to the simultaneously present basic amino (-textNH_2) and acidic carboxyl (-textCOOH) functional groups: 1. **At pH = 2 (Highly Acidic Medium)**: The abundant concentration of hydronium ions (H^+) protonates the carboxylate ion back into its non-ionized acid state (-textCOO^- rightarrow -textCOOH), while the amine group remains securely protonated as an ammonium ion (-textNH_3^+). Hence, product **A** exists purely as a **cation**. 2. **At pH = 10 (Highly Basic Medium)**: The high concentration of hydroxide ions (OH^-) abstracts protons from the system, deprotonating the carboxyl group into a carboxylate anion (-textCOO^-) and neutralizing the ammonium group back into a free amine fraction (-textNH_2). Hence, product **B** exists purely as an **anion**.
Protonation state structures of Valine across the pH spectrum
The flowchart maps the structural modifications of Valine when treated at strongly acidic (pH = 2) versus basic (pH = 10) conditions.
### Pattern Recognition Acidic environments (low pH) force positive overall charges onto amino structures (cation form). Basic environments (high pH) drive a net negative structure (anion form). This simple rule makes picking Option (1) immediate. ### Evaluation Rubric / Model Answer null ### Chapter Mix Class 12 Chemistry: Biomolecules

More Biomolecules Previous-Year Questions

Q67 jee_main_2026_21_jan_morning Amino Acids
Identify the correct statements. A. Arginine and Tryptophan are essential amino acids. B. Histidine does not contain heterocyclic ring in its structure. C. Proline is a six membered cyclic ring amino acid. D. Glycine does not have chiral centre. E. Cysteine has characteristic feature of side chain as mathrmMeS-CH_2-CH_2-. Choose the correct answer from the options given below:
  • A. textC and E Only
  • B. textB and E Only
  • C. textC and D Only
  • D. textA and D Only

Solution

### Core Logic A. Arginine and Tryptophan are indeed essential amino acids (cannot be synthesized by the human body). (Correct) B. Histidine contains an imidazole ring, which is a heterocyclic ring. So statement B is incorrect. C. Proline contains a pyrrolidine ring, which is a five-membered cyclic ring. So statement C is incorrect. D. Glycine is mathrmNH_2-CH_2-COOH. Because its alpha carbon has two identical hydrogen atoms attached, it lacks a chiral center. (Correct) E. Cysteine's side chain is a thiol group (-mathrmCH_2-SH), not a thioether (mathrmMeS-CH_2-CH_2- which belongs to Methionine). So statement E is incorrect. Correct statements: A and D. ### Evaluation Rubric / Model Answer null ### Chapter Mix Class 12 Chemistry: Biomolecules
Q44 jee_main_2025_02_april_evening Proteins and Amino Acid Sequences
A tetrapeptide "x" on complete hydrolysis produced glycine (Gly), alanine (Ala), valine (Val), leucine (Leu) in equimolar proportion each. The number of tetrapeptides (sequences) possible involving each of these amino acids is
  • A. 16
  • B. 32
  • C. 8
  • D. 24

Solution

### Related Formula textNumber of unique sequences = n! ### Core Logic A **tetrapeptide** is formed by connecting four amino acids through three peptide linkages. Since the problem specifies that complete hydrolysis of the tetrapeptide produces Gly, Ala, Val, and Leu in *equimolar proportions*, the peptide must contain exactly one molecule of each of these four distinct amino acids. ### Step 1: Calculate the Permutations The number of unique peptide sequences corresponds to the number of ways we can arrange these 4 distinct amino acids: textNumber of permutations = 4! = 4 times 3 times 2 times 1 = 24 ### Pattern Recognition Combinatorics in Chemistry: If we have n unique, non-repeating amino acids, the number of linear isomeric peptides is n!. If repetition were permitted, the number of possible peptides would be n^n (which would be 4^4 = 256 in this case). ### Evaluation Rubric / Model Answer null ### Chapter Mix Class 12 Chemistry: Biomolecules
Q jee_main_2025_02_april_morning Molar Mass Calculations
0.1mathrm~mol of the following given antiviral compound (P) will weigh times 10^-1mathrm~g
Antiviral nucleoside structural layout diagram for Q48
The diagram displays the full multi-cyclic skeletal structure of an antiviral nucleoside molecule featuring explicit iodine and fluorine atomic positions.
(Given : molar mass in mathrmg cdot mol^-1 H: 1, C: 12, N: 14, O: 16, F: 19, I: 127)
Numerical Answer. Answer: 372 to 372

Solution

### Related Formula Standard molecular weight calculation formula system: textMolar Mass = sum (textAtom Count times textAtomic Weight) textMass = textMoles times textMolar Mass ### Core Logic Let's tabulate and sum up the constituent atoms based on the verified structural formula layout : * Counting positions meticulously yields a molecular identity formula of mathrmC_9H_10FIN_2O_4. * Calculating the total molar mass: textMass = (9 times 12) + (10 times 1) + 19 + 127 + (2 times 14) + (4 times 16) textMass = 108 + 10 + 19 + 127 + 28 + 64 = 372mathrm~g/mol
Detailed skeletal atomic breakdown calculation diagram for Q48
The diagram displays the full multi-cyclic skeletal structure of an antiviral nucleoside molecule featuring explicit iodine and fluorine atomic positions.
### Step 1: Final Mass Scaling Find the mass of 0.1mathrm~mol of the sample: textWeight = 0.1 times 372 = 37.2mathrm~g = 372 times 10^-1mathrm~g Hence, the integer value for the blank box is 372. ### Pattern Recognition When counting atoms in nucleoside structures, remember that each vertex in the ribose sugar ring represents a fully saturated carbon component unless double bonds or heteroatoms are explicitly drawn. ### Evaluation Rubric / Model Answer null ### Chapter Mix Class 12 Chemistry: Biomolecules Class 11 Chemistry: Some Basic Concepts of Chemistry
Q37 jee_main_2025_02_april_morning Amino Acids Properties
Identify the correct statement among the following:
  • A. (1)\ textAll naturally occurring amino acids except glycine contain one chiral centre.
  • B. (2)\ textAll naturally occurring amino acids are optically active.
  • C. (3)\ textGlutamic acid is the only amino acid that contains a -COOH group at the side chain.
  • D. (4)\ textAmino acid, cysteine easily undergo dimerization due to the presence of free SH group.

Solution

### Related Formula Dimerization of thiol pairs yields a disulfide linkage via an oxidation mechanism: mathrm2R-SH xrightarrow[-H_2] R-S-S-R ### Core Logic Let's review each choice item factually layout-by-row: * Option 1 is inaccurate: Isoleucine and threonine contain two distinct chiral centers. * Option 2 is inaccurate: Glycine lacks a asymmetric center, rendering it optically inactive. * Option 3 is inaccurate: Aspartic acid similarly contains a carboxylic acid functional group along its side chain. * Option 4 is correct: Cysteine contains a highly active free functional -mathrmSH group that easily dimerizes to form Cystine through a disulfide loop matrix. ### Pattern Recognition Disulfide bridges formed by cysteine play a crucial role in maintaining the tertiary and quaternary structural configurations of complex protein folds. ### Evaluation Rubric / Model Answer null ### Chapter Mix Class 12 Chemistry: Biomolecules
Q28 jee_main_2025_03_april_evening Vitamins Classification
Fat soluble vitamins are: A. Vitamin mathrmB_1 B. Vitamin mathrmC C. Vitamin mathrmE D. Vitamin mathrmB_12 E. Vitamin mathrmK Choose the correct answer from the options given below :
  • A. C & D Only
  • B. A & B Only
  • C. B & C Only
  • D. C & E Only

Solution

### Related Formula Vitamins are classified into two categories based on solubility: - Water-soluble: Vitamin B-complex and Vitamin C. - Fat-soluble: Vitamins A, D, E, and K. ### Core Logic Categorize each given vitamin: - Vitamin mathrmB_1 (Thiamine) rightarrow Water-soluble - Vitamin mathrmC (Ascorbic acid) rightarrow Water-soluble - Vitamin mathrmE (Tocopherol) rightarrow Fat-soluble - Vitamin mathrmB_12 (Cobalamin) rightarrow Water-soluble - Vitamin mathrmK (Phylloquinone) rightarrow Fat-soluble ### Step 1: Select correct options Only C (Vitamin mathrmE) and E (Vitamin mathrmK) are fat-soluble. Thus, the correct option is (4). ### Pattern Recognition Use the mnemonic 'ADEK' to remember the fat-soluble vitamins. All other vitamins (mainly B-complex and C) are water-soluble. ### Evaluation Rubric / Model Answer null ### Chapter Mix Class 12 Chemistry: Biomolecules
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JEE Physics: Waves (+15.5%) | Electrostatics: Concentric Shells (-29.7%) | Modern Physics: Photoelectric Clones (+34.2%) | Mathematics: Definite Integrals (+18.1%) | Chemistry: Coordination Splitting (-11.4%) | JEE Physics: Waves (+15.5%) | Electrostatics: Concentric Shells (-29.7%) | Modern Physics: Photoelectric Clones (+34.2%) | Mathematics: Definite Integrals (+18.1%) | Chemistry: Coordination Splitting (-11.4%)